This study aims to examine the views and perceived limitations on the management of patients with mental illness in the community in a representative sample of general practitioners (GPs) illness. A postal survey was conducted among a random sample of 768 GP clinics in Singapore which yielded a response rate of 62%. About 68% of the respondent GPs indicated that they were managing mentally ill patients at the time of the survey, and anxiety and stress disorders were the most common mental conditions encountered by the GPs in their clinics. Over 90% of the GPs who were managing patients with mental illness felt that these patients were more comfortable receiving treatment from them than from a psychiatrist because of their confidence and familiarity with the GPs who provide accessible, affordable and less stigmatizing care. Serious mental illness like schizophrenia and addictions were regarded as the most difficult psychiatric conditions to managein a GP setting. Lack of adequate time and support from ancillary healthcare professionals, and need for training in the special medical needs of patients with more serious mental illness were perceived as key challenges in managing patients with mental illness in general practice.